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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea7dd2b8b9d7fe8a57798e62d163be610ec0b7e8f21f1809b9c56652dfbca7d9' 
  AND token = '6J7NpFC/A5Di+4+7A914xuzHuxc+Cnb9TtLk6u+8mpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}