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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7989991af58e87e4d1574a600b2005842c67710a1cfc192be99fd1a55bb22120' 
  AND token = 'ZO64xa7NPidi7C1Ge0LmrXu6VwwmVKhrCRQhO29PQaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}