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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7ef5ac008ae317a24ff3124b0a4cc9ec933ca429bab0c1657abaaf3010631dd' 
  AND token = 'V0+EVz0xbMPbiUb4CYlFwMqYe7hhZZPa9zYD7hAGE6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}