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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99ddf4fd4582f71b4be79d46aca8f8e694e955ccc0eb13f872b1c30bebfed10d' 
  AND token = '4wQ0kCmzrxwoDYalOAdnEojaEvXIe5AnWN0mfCPtbgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}