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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd7a529e2dbfa896052bc3fdcf47818329c31e1e21d5f9eef70a2c2305c702ad' 
  AND token = 'Ffwo7kuUJETwChxo7rwlUMhYiLUtKxUP2XbtSlDX+Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}