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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bde296c7f71d4164c7cd52fb2389aa063ea09531623a2953aeff73b693e3bc28' 
  AND token = 'JdbesMOC2UIpeMQHnhb1d8B+D2MH10orKSDyxaa0YQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}