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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dafd36e1446a03a1946b8e5d2772c05cccd15ec2a093a9986e5c7a1321b35e40' 
  AND token = 'PyMhZyzFaQaf81cym0golrf4pncWuKYVeE+WjiyHXC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}