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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1d5e16d72ab131acb089c521f9a82659c4d6900f8037d39df6e62032e711e21' 
  AND token = 'xxrgMQtt0p/1AgG5+t6Bhypevwm2yf2ToIXC1eE/y2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}