SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61a04d62b7e7721bc3478caac3e4f1539619534a9727826f14e74a8665700f88' 
  AND token = '0X6z+A+Xyab1DTXtaGit0j9hdrxFcwPNgVpT1wKJADA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}