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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19809b355cdc6316b209fafc6f8f1d26772d98319bc07ad63900037becf351c3' 
  AND token = 'Mqz0n/PEBGY4g7DU4TaofDI64T5je4QxfrTwOVG1+Qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}