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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f162ba6bc866ae8ede126c71b716ac85b9ad6220183d9812b5e78e4f188c6c2' 
  AND token = 'U04YkgvmKC7FIg6d0uGG/NL99U0UAiQvzrlQfqyC05M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}