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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86ddcd84c4e347cd6225414dd059fb0cf585c3346ec4ec2553b03dd0d042cee4' 
  AND token = 'clf9oMFw8DuM5/ehpfTZ0WI2fP1/JNvMBECurlZ6cDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}