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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bebd0c225534e19778e8d22a11c89739ca4c4c849bbbb47b7697842a3aca2d3' 
  AND token = 'q6ehiE5Q7p+mkrU3YeHhNxW9vuU6xCz+1/4AQWUMBd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}