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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380aa5bf518edacb0e30e3b202da79b39a59d51ee48e4b41a5d00b0571bf4c28' 
  AND token = 'jqGheIZF3/CP9vloMyhq28jQUFhY6TL55LXTqthUpw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}