SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a749a4f93272339b4f70929c8041e5dfb96c992f8e1236e841666c86193c7f1' 
  AND token = 'fxrUeUkQZYZkt3um0rPah6YhWUakL7aOERNVLA2QcXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}