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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456ddabb45a9b5b3c399e21f1882fba8e14b9ea3d24996519dc06702c89621d2' 
  AND token = 'LqSQssMhV24klLhOXYf/Y714i+uUUlcTHkU8cKjAf08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}