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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11ad598246af6085e0ca22edc1efa9f6504635df668b0c3a29988a4f679a3209' 
  AND token = 'aGioFMaleKHWeOy1MmDHSF9xRGiBv+t8fRVOgZEuJAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}