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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ff69bd993736613ca65d24e39527ef4b54c4922447175a86bf91c5bac3e61e1' 
  AND token = 'jBnnWMN9v2dD86pBTYlHediAXUVOiT/Hce9DG6UCdzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}