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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa43eef018ea113670ea1a7728f8d26ef07c79272d72ca07084b9bd28f100f77' 
  AND token = 'vpGG+6KYbz2OAhcoYaffJNS6o9zFQYbjWrM/hotvQ6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}