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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4da9485d3b906d707ddf6aa10cf2c204328147ee8a22dc723af2d96c1d738d6' 
  AND token = 'TBPdlpWy6JtyJxUqgSDXLBLa0z5M+VhZ38rLviJ4isA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}