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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27c073c05083d27b2aec102ee3fea8d629e89c8c0f35353513a4b3fd96ec631d' 
  AND token = 'DwcwUspKH1085SQKiitgvmUIa9KhtqVm/VR1wX1M8pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}