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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b915be9bbc8d151c6c1289a1c50f48d7b2c0a33238d0bb5c182799fb9d51f3f' 
  AND token = 'Cn7iU7nee6OTOMdW02LI9Awr5yHjrnJ907W0jl2XNgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}