SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fffa33dd8b67c7b910f3d16cd5a298ca8149ee9071f3bdb952250c40721c665b' 
  AND token = 'AYR/CCg634IFtYBGERALms3OIOBizu9k+suv/DHFF7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}