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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26f64e226607b0091ce56f50430815294df7eb16f5f46950de52a6d16fbdd511' 
  AND token = 'aTmMqoNw+5JTZuzBl61eFEzCyBmirn/bTx8K0wnmnZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}