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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81067378cb3b652a93382be1a1a354d0b017d26870e1351901df5374ca97a393' 
  AND token = 'xmYoO0I3fyfNCS259edqpY0N8iXBSte5+PYS2LdcQ+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}