SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e726527d5d2806caafe4320aa10c43ad750296e875fc141a64e25ac37371a056' 
  AND token = '2h6oPAn7j7UOS6zHIRmRgvemazkbP0wJMJPkQsa7dk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}