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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c780a349f266fdcf0670c333ea7ba07f559901ef92d23090500c0f7dd3ce8c8' 
  AND token = 'e3C3uDIu4HlsCtx9r2taQjd2lJAxi0DonW/+MnmO9Lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}