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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '083518e4cf853f034fcf47f87d62206fdac89d525c6f02929043b33b5947c8d0' 
  AND token = 'IbZ3NDBoI1a4GfPUMbB1kTkXfarnyd6EcVaKuiHOUHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}