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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd106ce369b0487f277b6580e0346179f189e14643d82dad5bb97c67d750cf3e4' 
  AND token = 'yojJAPDtJVYTNyGmGKvN9Eq2g4d2CDIkcbDuIikjl8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}