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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f757f2f811fb36c64015e42bb419bd08a0f3c92abef652f1c336c4402e3c5c85' 
  AND token = 'uD33hlILmYHZ/fVb1Ton3WU7s8x+oVQcIy67uCp8il4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}