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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '355fe74bb3e7ffe8ebbe9cd7e72b27be79baa4488be824ac463057cf1a87ffc6' 
  AND token = 'PJ4DYh2q9M0qFp5faAOSV0Ymu/9W4X5wQcoAv8vC+UY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}