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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bea33c003f6a9fa9e9fd4c098d9ead712721753ab50bb7900ff93374cf5e8cc6' 
  AND token = 'I2e53T4fVCO8PVro2QDOjNiW+gdndXlkvjOdpQUlv7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}