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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fca1f018ead1f874465254d37d00e9c2b334310f881e9474d96829f21890362b' 
  AND token = 'yZ+k9aQBAtunuNd5RkKJI95rLATiYP7DCXXsQ0pS9Yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}