SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1f1e8e829b6ee7fac764863c1849923f10a42dbe78836896b26a79d0501c53f' 
  AND token = 'tz7SurKHmfFp4ONW+u+WHWAr8MferaZQzCK/wQ4PDfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}