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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b19129b43a188c8405334a6e3e960878c0dc024832eca5af6f698a831b9b960d' 
  AND token = 'HTjxVQ3XlqCVlZAO8fHZlkd2hUBxaZB9dV25tS0HpmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}