SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8db8c4c66f49399e6f1a64cf1d66a4e66709a15a84e94c504a70a0e577407cb6' 
  AND token = 'LbXz77rxcDKhPwZ64j4Mmo+sxAumhmWtBzmQ+6i6ygo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}