SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888074ea26bd77f58667498531fbdeb8a9878c0081b18fc9cb61dd9a5d55bdc5' 
  AND token = '3/hMcFHVfB8sb5iE2Uzw1pFMU4XcOdn49R0rcXhWojo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}