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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a3845e37bcb99273f5c418493878e8f10d1584abdeced3a7c4a364df6e0fc27' 
  AND token = 'W7NtyzbYdayUW896+6Wag0iMIsBDzZjWsOyNLFX/g0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}