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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46aaa7068ebb3cd28c7e332855c80f73d56fa3387a781951a5e52bba73885b3b' 
  AND token = 'qbukQw2mwbrY6939hPszKD+PO19cRvcyNoFApQbAICI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}