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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0d6dbe6b86a7285a61fa483c5c0369d0b5228b9e479a5ccbb5da0602d4c7705' 
  AND token = 'AFZNuwj8sr4Xi8lPeniRJEz9PvSkmsgaE0PmXFswQb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}