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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0e80c51c5ac324715308f00851060d9fee13bd2cf7564cc469a89d5106826d1' 
  AND token = 'jeqGbql2cK0B6IivXK+nDR7VQJIv5tWYfiRewQ2ek/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}