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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e11b60f7ec071dd4aa07445d1d3bae6c77ae36f3c2df8513807284c6eec18420' 
  AND token = 'JTb3lHrRPPqlytGtK8nB0jHi6oRYOjSy5Dn+TgbcuBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}