SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '748a7cf3bbcb7ed34dc1750a459d278f9083383c25566f1f176e57b557946a82' 
  AND token = '+Y/xhSROvy79na51ZouefuKmaZ47NpYJ6Caq65m8Ag0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}