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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd84d0230cd9fe24a3e0d139c06b22c1c60159b31a08e2af719e8911ce47e7e06' 
  AND token = 'bm9nH1XnOpSVrbIzjqcvAvqLGSmcjuuSXj0xzTtaTkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}