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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88500bccde5f2a25808df675d51a06018768f28722c14a5db5c03bec667fbd5d' 
  AND token = 'PKnIbV5RFUisDSsq/g1Wp6B7D4n+lG08P90vZ7GAr5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}