SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee8723329298506f3006349c486b5e10d27e2436ab473122c8f01460b5a5e6a6' 
  AND token = '1r4W07EUhjvxDT6nRr1UScNbys6dr2PdhJooCBq6+iM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}