SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c58e5dff65668591c150323aa0f99795783c8ad626ac35ad05d9952b4ad5a314' 
  AND token = 'Zuc2i4vNc/Pk0dpOm/JPCk4WgVVFeAPjpD+hZklPocU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}