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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e3c464946c705ef464926a52a5770d7eee32cec9ab4bd0459c59cfc66bd3d9c' 
  AND token = 'ZT0A2IEO5siB/oA2jt2W5qiwr5w/phBPmWWbIt19sUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}