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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4516f02f041b79aa6a4b876ef4cdbdff7232484d9e8133c4b4e9b750aa56b31' 
  AND token = 's7MciNVopMTe4a9C3tT4Kcs19ksmzy0t3jFJ6+RE8rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}