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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f43c492ffa3ff4106242bdd739a1e584ff288f3d660bb74e870d212e0bbfc8d3' 
  AND token = '3c7GyJKdgsRVxnoV21KSTElSk6HzxTyXy5ZOwTGkYbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}